The Great Lakes Eagle Health Project (formerly the Wisconsin Bald Eagle Bio-sentinel Program) is a collaborative program that has monitored bald eagle contaminant levels in WI since 1990. The purpose of this project is to monitor exposure patterns of both legacy and emerging contaminants in nestling bald eagles as well as illustrate the utility of bald eagles as monitoring tools for contaminant exposure and ecosystem health. Data from this monitoring program suggest eaglets along the middle section of the Wisconsin River have elevated levels of per- and polyfluoroalkyl substances (PFAS) compared to other populations. Other emerging contaminants that have been detected include industrial compounds (phthalates) and endocrine disrupting chemicals (Bisphenol-A). This project provides natural resource managers with a snapshot of contaminant exposure within a given ecosystem. They have illustrated that bald eagles can be useful and reliable indicators of contaminant exposure, environmental change, and ecosystem health.